Release 3.1 (Sept 2017)


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Description:

PolyA_DB version 3.1 catalogs polyA sites (PASs) in genomes using deep sequencing data.Gene annotations are mainly based on NCBI Gene and RefSeq databases, and supplemented by the Ensembl database. Strand-specific RNA-seq data are used to extend the 3' end of genes. PASs are identified using data from the 3' end region extraction and sequencing (3'READS) method. Syntenic regions across human, mouse and rat are used to annotate conserved PASs in mammals.

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References:

Wang, R., Nambiar, R., Zheng, D., & Tian, B. (2017). PolyA_DB 3 catalogs cleavage and polyadenylation sites identified by deep sequencing in multiple genomes. Nucleic Acids Research.
Hoque M*, Ji Z*, Zheng D, Luo W, Li W, You B, Park JY, Yehia G, Tian B. (2013). Analysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing. Nat Methods.10:133-9.
Zheng D, Liu X, Tian B. (2016). 3'READS+, a sensitive and accurate method for 3' end sequencing of polyadenylated RNA. RNA.22:1631-9.



Please contact Ruijia Wang/Bin Tian for questions/comments/suggestions.